YBB 6006-2012 English PDF (YBB6006-2012)

This method applies to the determination of residual solvents in pharmaceutical packaging materials. This method is based on the gas - solid balance. Take a certain area of the sample. Place into a sealed container. Under a certain temperature and time conditions, the organic solvent resided in the sample is heated and evaporated. After the equilibrium is reached, take headspace to quantitative inject into the gas chromatograph for analysis. Use the maintaining time to perform qualification. Use the peak area to perform quantitation. Determine according to the determination of residual organic solvents (Part 2, Chinese Pharmacopoeia 2010 edition).